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Important considerations include: Limited long-term human data Individual variability in response Potential side effects Need for ongoing medical supervision Because research continues to evolve, realistic expectations are essential

Mitochondrial dysfunction in autism spectrum disorders: a systematic review and meta-analysis

Lee JG, et al

Chan HL, Chan CK, Hui AJ, Chan S, Poordad F, Chang TT, Mathurin P, Flaherty JF, Lin L, Corsa A, Gaggar A, Subramanian GM, McHutchison JG, Lau G, Lee S, Gane EJ

Regarding PD, a Japanese casecontrol study has shown that low intake of vitamin B6 was associated with an increased risk of PD (69)