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The predominant mechanism involves Tf/TfR1-mediated endocytosis, where transferrin-bound Fe 3+ binds to TfR1 on endothelial cells, is internalized into endosomes, acidified, and subsequently released into the cytosol via DMT1-mediated transport

Neocryptotanshinone ameliorates insufficient energy production in heart failure by targeting retinoid X receptor alpha

Molecular features of the ligand-free GLP-1R, GCGR and GIPR in complex with G(s) proteins

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Rippa, S., Zhao, Y., Merlier, F., Charrier, A