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Consider it more of a short-term tool than a long-term solution

Growth media was replaced with binding buffer [DMEM containing 25 mM HEPES and 0.1% (w/v) BSA] containing 0.1 nM [ 125 I]-exendin(939) and increasing concentrations of unlabelled peptide agonists

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Because tirzepatide activates both GIP and GLP-1 receptor systems, it provides a useful research tool for examining receptor cross-talk, signaling bias, and coordinated regulation of metabolic pathways in controlled experimental environments

Jeffrey Lee, MD, a double board-certified plastic surgeon and founder of JL Plastic Surgery in Boston, MA, who was not involved in the study, spoke to Healthline about these hidden side effects, why they may occur, and what people may misunderstand about GLP-1s from social media posts