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Most patients experience noticeable weight regain within 24 weeks of stopping, with average loss of 5070% of progress over 6 months

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Renal or hepatic impairment may necessitate lower starting doses

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There are several different GLP-1 medications currently approved for weight loss in people with obesity, including: Liraglutide and semaglutide are GLP-1 receptor agonist medications, while tirzepatide is a dual GLP-1 and glucose-dependent insulinotropic polypeptide (GIP) receptor agonist medication