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GHK-Cu for Wound Healing and Post-Surgical Recovery In a 2023 study, GHK-Cu combined with hyaluronic acid elevated collagen IV synthesis by 25.4 times in cell models and 2.03 times in ex-vivo skin tissue

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Galvano F, Li Volti G, Malaguarnera M, Avitabile T, Antic T, Vacante M, Malaguarnera M

Abbreviations AA : Amino acid ANOVA : Analysis of variance AUC : Area under the curve BCAA : Branched-chain amino acid BMI : Body mass index ESI : Electrospray ionization IFP : Infrapatellar fat pad KOA : Knee osteoarthritis LDA : Linear discriminant analysis LI : Level of identification OA : Osteoarthritis PLS-DA : Partial least squares discriminant analysis QC : Quality control RA : Rheumatoid arthritis ROC : Receiver operating characteristic SE : Standard error SF : Synovial fluid TKA : Total knee arthroplasty TOF : Time-of-flight VIP : Variable importance in projection References Kontny E, Zieliska A, Ksiopolska-Orowska K, Guszko P (2016) Secretory activity of subcutaneous abdominal adipose tissue in male patients with rheumatoid arthritis and osteoarthritis association with clinical and laboratory data

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