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Using two groups (i.e., Semaglutide and Tirzepatide), two measurements (pre/post), a medium effect size (Cohens f = 0.25), alpha of 0.01, and 95% power, we required 76 participants

These medications may affect appetite, fullness, digestion, and blood sugar regulation

Semaglutides clinical profile is well-documented, with known effects related to gastrointestinal function and appetite regulation

We could also consider a randomized study of patients who have failed bariatric surgery between a second surgery group and a drug treatment group, Avignon said

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