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No human trials on AOD-9604 for joint health have been published

2), while uptake and catabolism of fructose and ribose yield fructose-1-phosphate and ribose-5-phosphate by fructokinase (albeit most tumors except hepatocellular carcinoma express low activity of this enzyme) and ribokinase 9 , respectively

Nelson, K.K

Moreover, the many technologies employed in the manufacturing of herbal extracts and formulations pose a challenge to the quality control of their active plant metabolites

The main issue is concentration: the great majority of supporting studies come from Khavinsons institute and affiliated authors, with limited independent replication and few rigorous double-blind randomized controlled trials