Were advocating for all countries to have these medications because theyre so effective and they can help so many patients, said Carel Le Roux, expert advisor to Lindus Health, a clinical research organization, and director of the Metabolic Medicine Group at University College Dublin
The weight loss achieved with GLP-1 therapy appears central to hepatic benefits, as weight reduction of 710% consistently improves NAFLD across multiple intervention studies
Important safety considerations include risk of pancreatitis (treatment should be discontinued if suspected), gallbladder disease, and potential worsening of diabetic retinopathy in patients with pre-existing retinopathy who experience rapid improvement in glucose control (particularly with semaglutide)
Interestingly, this side effect was more common in individuals with darker baseline skin and in those who took many doses
But the before and after principles are the same: the more significant the pre-treatment GH decline, the more dramatic the recovery
