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Intriguingly, recent research highlights that ionizing radiation can trigger ferroptosis in certain cancer cells by amplifying lipid peroxidation [186, 187]

Furthermore, this result suggests that non-tumorigenic tissues or cells in the tumour microenvironment with high GGT activity can drive tumour growth and progression by catabolizing GSH and supplying amino acids in a paracrine (or endocrine) manner

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A human liver chimeric mouse model for non-alcoholic fatty liver disease

The measurement of organic acids provides a way for the physician to perform a functional assessment of the patient nutrient status