The authors hypothesize that this paradoxical worsening is due to a cytokine imbalance, similar to what is seen with the exacerbation of disease after administration of biological treatments like anti-TNF, which increases interferon (IFN)- release and leukocyte chemotaxis [25]
Cosmos Study - Collaboration March 3, 2026 Dual-Team Study Team A:Kersten Bartelt, RNKendall F Moseley, MDJoe Deckert, PhD Team B:Dave Little, MDEmily Higgs Key Findings Among adults with type 2 diabetes, osteoporosis risk was lower for patients prescribed a GLP-1 than for patients who were not prescribed a GLP-1, when compared to a baseline of stable-weight patients who were not prescribed a GLP-1
8 Nguyen et al 9 reported that 671,959 patients underwent gastric bypass procedures in the United States from 2003 to 2008
2 To understand how semaglutide (GLP-1 RA) medications work, we need to talk about the receptor in your body theyre mimicking: GLP-1
With the increasing use of glucagon-like peptide-1 (GLP-1) receptor agonists in the management of T2D and/or obesity, the potential impact of these drugs on the kidney has become an area of intense investigation