do not combine dpp-4 inhibitor with glp-1 receptor agonist guideline The pharmacology of inhibitors is divided into primary do not combine glp-1 receptor

How to safely switch between GLP-1 medications You can switch between GLP-1 medications if the GLP-1 you are currently taking is not showing significant results despite dosage adjustments, you are experiencing intolerable adverse effects, or you want to change dosing frequency (from weekly to daily or vice versa)

10.1111/j.1464-5491.2007.02058.x

Prescribers should use their independent clinical judgment when determining appropriateness for individual patients

10.3390/ijms25042251 Int J Mol Sci

Although there is evidence that DPP-4 inhibitors confer cardiovascular safety and renoprotection, the potential risks of hospitalization for heart failure and acute pancreatitis are disadvantages to their use as add-on therapy