GHK-Cu is generally stable but can potentially be deactivated or cause irritation when combined with certain strong acids (like high concentrations of AHAs or BHAs, particularly Ascorbic Acid/Vitamin C in low pH formulations) and some direct acids (like L-Ascorbic Acid)
Besides various therapeutic and pharmacological treatment options, numerous procedural treatments including laser therapy, light therapy, and microneedling have been considered in melasma treatment (Kwon et al., 2019)
PCR is another valuable method to assess receptor expression, although it does not typically provide cellular resolution, unless laser capture microdissection is also applied
PMID: 98 PuppeJSeifertTEichlerCPilchHMallmannPMalterW
Once your side effects subsides, you can gradually reintroduce more fiber back into your diet until you are enjoying a moderate, but not excessive, amount