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Within the cardiovascular system the actions of GLP-1 are exerted cardiac endothelial cells and cardiomyocytes, vascular endothelial cells and smooth muscle cells (VSC), as well as VSC within the glomerulus of the kidney

Berberine also reduced tail vein blood glucose levels, boosted intestinal L cell GLP-1 synthesis in serum samples, and raised colon tissue GLP-1 expression in mice

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