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To analyze the divergence or similarity in generated models, the structures were superposed in order to calculate the percentage of structural overlap and RMSD values (Table 8)

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For example, HepG2 cells exposed to 20 mM APAP for 24 h showed only a minor (8%) reduction in GSH content, a minor increase in protein adducts, no mitochondrial dysfunction and only a 2-fold increase in lactate dehydrogenase (LDH) release [142]

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Akakpo JY, Ramachandran A, Curry SC, Rumack BH, Jaeschke H