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Prez-Velasco MA, Bernal-Lpez MR, Trenas A, Ricci M, Lpez-Carmona MD, Garca de Lucas MD, Gmez-Huelgas R, Prez-Belmonte LM (2025) Efficacy of once-weekly semaglutide in patients with heart failure with preserved ejection fraction, obesity and type 2 diabetes

Side Effects and Safety Concerns Common Side Effects Nausea Vomiting Fatigue Diarrhea or constipation Acid reflux These typically fade within the first 46 weeks as your body adjusts

Regular Physical Activity: Incorporating consistent exercise into your routine

National Digestive Diseases Information Clearinghouse

Slow digestion from GLP-1 may impact how fast levothyroxine is absorbed