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Melatonin has been reported to bind KEAP1, thereby disrupting this interaction and permitting NRF2 to translocate to the nucleus where it can activate antioxidant response element (ARE)-driven gene expression (41, 62, 63)

The application of advanced analytical techniques, including high-performance liquid chromatography and mass spectrometry, has greatly improved the detection of pharmaceutical compounds at trace levels, enabling researchers to identify a broad spectrum of pharmaceutical contaminants in complex environmental matrices [106]

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The combination of Glycerin with a touch of Dimethicone gives this serum a silky texture that feels almost luxe when applied