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The first one was a 72-person 2008 study looking at cissus quadrangularis for weight loss
10.3390/biom7010016 95 SteinerJ
That link is part of why gut flares may come with joint aches, skin issues, or tiredness
10.1519/JSC.0b013e3181c7c299 36
The questions that remain unanswered include the actual prevalence of sexual side effects (we do not know if it affects 5 percent or 30 percent of women), whether certain doses are more likely to cause sexual dysfunction than others, whether compounded semaglutide formulations produce different sexual side effect profiles than brand-name versions, whether specific pharmacy sources or compounding pharmacies produce formulations with different tolerability profiles, and whether pre-treatment screening can identify women at higher risk for sexual dysfunction on GLP-1 agonists
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