Liposomal formulations, reduced glutathione variants, and alternative delivery routes (IV, intramuscular, nebulized) bypass this limitation but require clinical administration
Cristal Hill Department of Internal Medicine, Southern Illinois University School of Medicine, Springfield, United States Contribution CH, Conception and design, Acquisition of data, Analysis and interpretation of data Competing interests The authors declare that no competing interests exist
Often described as an exercise-mimetic compound , SLU-PP-332 has been shown in pre-clinical models to elicit molecular and physiological responses similar to endurance trainingmaking it of particular interest in studies involving metabolic health, mitochondrial function, muscle endurance, and age-related energy decline
This bidirectional gene modulation profile is unmatched by any other single compound tested in the CMap database
The formation of dityrosine was further supported by the steady-state fluorescence measurements