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Their further research showed (127) that GCK could inhibit the abnormal activation and differentiation of T cells in CIA and AIA animal models, and its potential molecular mechanism might be the inhibition of CCL21/CCR7-mediated DC migration and signal transduction between T cells and DC

doi: 10.2217/nnm.15.29 179 ZhangSLangerRTraversoG

Preliminary research also suggests that NAD+ may play a role in supporting sirtuin activity proteins being studied for their involvement in healthy aging