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Suspected side effects can be reported via the MHRA Yellow Card Scheme (yellowcard.mhra.gov.uk), which helps monitor the safety of medicines in the UK

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This is one of the most common pharmacy defaults, especially for patients who order larger vial sizes to reduce per-dose costs

Stratified analyses in higher-risk groupssuch as older adults, individuals with sarcopenic obesity, or those with elevated inflammatory burdenmay further determine whether adaptive thresholds differ across metabolic contexts