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This synergistic effect is distinct from directly increasing hormone levels

Does Semaglutide Make You Thirsty

doi: 10.3390/medicina55070368, 17

The honest answer to the question is indirect: semaglutide has been shown to reduce congestion-related symptoms in one specific population studied in a randomized trial, and weight reduction can plausibly ease some forms of dependent lower-limb swelling, but neither of those makes it a treatment for edema