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The primary contraindication in women is pregnancy or breastfeeding: sermorelins effects on fetal development are unknown, and both peptides should be discontinued at least 8 weeks before attempting conception

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doi:10.1186/1472-6963-10-159 Sarwer DB, Gasoyan H, Bauerle Bass S, Spitzer JC, Soans R, Rubin DJ

The therapy is not viewed as a shortcut but as part of a comprehensive metabolic strategy, including nutritional support, diagnostic testing, and real-time risk evaluation