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While the comproportionation reaction is a well reported redox cycling chemical mechanism, in this instance the triad model does not require the additional comproportionation reaction to accurately replicate the experimental OCR profile, suggesting that the comproportionation reaction is not mechanistically integral to the production of ROS through a quinone-based redox cycle

This is because these ingredients work synergisticallyvitamin C helps regenerate glutathione, whilst other brightening agents target different pathways in melanin production

Glutathione 600 appears in the technical documentation combined with vitamin C, TRX, glycolic acid and sodium pyruvate, underlining its value in professional brightening, antioxidant and depigmenting support routines

[DOI] [PubMed] [Google Scholar] 10.Tietze F

Tuo et al., 2024)