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As a further factor likely to influence ligand-receptor complex stability, the metalloprotease endothelin-converting enzyme-1 (ECE1) was also shown to colocalise with internalised GLP-1Rs, and presumed to facilitate GLP-1R recycling via proteolytic processing of endosomal GLP-1 (96), as previously shown for other GPCRs (97)

Sources: Source 1: Action and resistance mechanisms of antibiotics: A guide for clinicians Source 2: Gut flora in health and disease Source 3: Impacts of Gut Bacteria on Human Health and Diseases Source 4: Potential Role of the Microbiome in Acne: A Comprehensive Review Source 5: StatPearls: Antibiotic Resistance Source 6: The pH of the skin surface and its impact on the barrier function Source 7: The Acid Mantle: A Myth or an Essential Part of Skin Health