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Strikingly, in agreement with our previous results in C57BL/6J mice, insulin sensitivity as assessed by an intraperitoneal ITT was significantly improved only in CR-fed female mice, and not in DL-fed female mice, regardless of genotype (Fig

Cancer and Treatment Support: The high glutamine intake by cancer cells to grow and multiply has also caused researchers to wonder about the influence of glutamine metabolism on cancer progression

This transport is essential for cancer cells to maintain their antioxidant defense by facilitating cystine uptake, which is subsequently reduced to cysteine and used for GSH biosynthesis

Gut 65 , 144154 (2016)

d , Western blot of Gpx4-knockout Pfa1 cells overexpressing exogenous human WT or R152H GPX4, Gpx4-knockout Pfa1 cells overexpressing exogenous murine WT or R152H mScarlet-tagged GPX4, and Gpx4-knockout HT1080 cells overexpressing exogenous murine WT or R152H mScarlet-tagged GPX4 using GPX4 and GAPDH antibodies