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Significant elevations in short-chain and long-chain, but not medium-chain, acyl-carnitines were found in the ASD individuals with consistently abnormal acyl-carnitine panelsa pattern consistent with the PPA rodent ASD model

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480,481,482,483 The role of the UPS in autoimmune diseases The UPS regulates processes relevant to autoimmune diseases, such as antigen presentation, cytokine production, T-cell receptor signaling, and inflammasome activation, making it a central player in immune homeostasis and inflammation

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Ice packs should be applied every two hours for twenty minutes for the first 48 hours