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The common and reported Wegovy side effects include nausea, diarrhea, vomiting, constipation, stomach (abdomen) pain, headache, tiredness (fatigue), upset stomach, dizziness, feeling bloated, belching, low blood sugar in people with type 2 diabetes, gas, stomach flu, heartburn, and runny nose, or sore throat
This creates a flatter pharmacokinetic curve with lower peak levels and higher trough levels, potentially reducing the intensity of receptor desensitization at peak concentrations while maintaining more consistent receptor occupancy throughout the week
It may help some individuals, particularly by reducing meal-driven urgency, but it carries a real risk of worsening constipation and other GI side effects that overlap with IBS
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