These theories include genetic variations in the transporter, stimulation of the intestinal secretion of serotonin, production of lactic acid by the intestinal mucosa, bile-salt malabsorption, and changes in the microbiome [188]
But I think we need to do it safely, carefully, and its going to take us time to think through all the governance, through all the guardrails and how do we do it in a way that really preserves the quality of care
At least two clinical trials are currently ongoing for OUD, investigating both liraglutide (Freet et al., 2024) and semaglutide (Freet et al., 2025)
How to verify quality Third-party laboratory testing using HPLC and mass spectrometry provides definitive peptide identification and purity analysis
Acknowledgements The authors are indebted to Mr Ronen Shechter from the Barzilai University Medical Centers information division for his assistance with digital data availability