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Several commenters indicated they desired an enhanced focus on enforcement by CMS to ensure widespread compliance with the HPT rule in an expeditious and efficient manner

For example, Saxenda can only be taken by patients who have a BMI of 30 or above (27 or above if you are at risk of weight-related medical problems), whereas Victoza can be taken by suitable type 2 diabetes patients no matter what their BMI is

As a result, fermentation of food begins before it has been thoroughly digested and absorbed, which can lead to gas formation

This imbalance causes damage to proteins, lipids, and DNA

In the UK, it is approved for use in adults with a BMI of 30 or more, or in adults with a BMI of 27 or more who also have another weight related condition, such as high blood pressure or type 2 diabetes