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In taurine and hypotaurine metabolism, GAD and CSAD, molecules that are responsible for the synthesis of both taurine and hypotaurine, and FMO1 that is involved in the synthesis of taurine from hypotaurine were selected

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Colonic biopsies from these patients also show reduced GLP-1R expression, suggesting that decreased GLP-1 and GLP-1R expression may underlie the efficacy of ROSE-010 in alleviating IBS-C abdominal pain [61]