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To assess the efficacy of combination treatment, tumour-bearing mice were treated as above with 5FU + metformin and CC3-quantified, showing an increase in average cell death per tumour per mouse with combination treatment (Extended Data Fig

Expression of airway remodeling proteins in mast cell activated by TGF- released in OVA-induced allergic responses and their inhibition by low-dose irradiation or 8-oxo-dG

2017 Cell study used 5 mg/kg intraperitoneal injection three times per week in aged mice, with treatment periods of several weeks the three-times-weekly dosing suggests the peptide maintains sufficient functional concentrations for at least 48-72 hours per dose (PMID: 28340339)

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Owing to the high cost of components such as cysteine and yeast extract, the original YCK50D medium formulation was considered economically unsuitable for large-scale industrial fermentation