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Dendritic Spine Formation and Neural Connectivity in Preclinical Models Dihexa has been evaluated in multiple preclinical models of cognitive impairment: Scopolamine-Induced Amnesia: Scopolamine blocks muscarinic acetylcholine receptors, producing temporary amnesia in rodents

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Inclusion and exclusion criteria We included potentially relevant studies if they met the following inclusion criteria: (a) original randomised clinical trials with either parallel or cross-over design

McClean et al