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Women who were already receiving hormone therapy may have differed from those who were not in ways that the matching process did not fully capture: differences in baseline metabolic health, in how long they had been postmenopausal, in their physical activity levels, or in other clinical factors that influence GLP-1 responsiveness

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We received feedback from commenters that the current component percentages published in the PFS were developed using magnitude estimation and cross-specialty scaling and that there is not any reverse engineering of work and time that can be performed to develop a better percentage of pre-, intra- and post-operative work than what is currently published in the PFS