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Bone marrow stromal cells cultured in medium supplemented with low selenite concentration exhibited ROS accumulation along with the reduced expression of GPXs, TXNRDs, and other selenium-independent oxidoreductase enzymes, resulting in micronuclei generation which is an indication of chromosome damage 126

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Funding This research was supported by the Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education (grant number: NRF-2019R1F1A1054111 (JS), NRF-2019R1I1A3A01058861 (OK), and NRF-2018R1A2B6001104 (Y-KK)

J Invest Dermatol 97(2):273280 Stringari C, Wang H, Geyfman M, Crosignani V, Kumar V, Takahashi JS, Andersen B, Gratton E (2015) In vivo single-cell detection of metabolic oscillations in stem cells