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AMSTAR 2 assessments indicate that the existing evidence is limited by methodological shortcomings, including incomplete reporting of excluded studies, suboptimal literature search strategies, and insufficient evaluation of how bias in primary studies may influence meta-analytic estimates

Focus on the overall dietary pattern (more fiber, fewer processed meats) rather than a single metabolite, and dont use TMAO alone as a reason to avoid fish

C., & Chini, E

It wont replace healthy habits, but it may enhance the results of the ones you already have in place

When in doubt, a healthcare provider may suggest testing just to be safe