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Important safety considerations include caution in patients with diabetic retinopathy, particularly with semaglutide, as rapid improvement in glucose control may temporarily worsen retinopathy

Toll-like receptor (TLR)-mediated nuclear factor-kappa B (NF-B) signaling is a key regulatory mechanism in the pathogenesis of sepsis, as it is essential for inducing the expression of inflammatory cytokines and inducible NO synthase (iNOS)-mediated oxidative stress, respectively [118,119] (Figure 9)

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[DOI] [PMC free article] [PubMed] [Google Scholar] 67.Yang X., Feng P., Zhang X., Li D., Wang R., Ji C., Li G., Hlscher C