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To further illustrate the effect of SeC@PA MN(+) on macrophage polarization, the infiltration of macrophages into wounds was investigated using immunofluorescence staining

Concurrently, the focal adhesion pathway was hyperactivated, as evidenced by the upregulated expression of key adhesion and cytoskeletal linker proteins, including Actn1 , Tln1 , and Rac2 (3.1- to 8.5-fold), suggesting enhanced cell-ECM adhesion signaling under HFD

However, it is important to note that many peptides remain classified as investigational

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