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Editorial assistance and support were funded by an independent grant from Alfasigma S.p.A

The STEP clinical trial program reported that approximately 74% of participants on semaglutide 2.4mg experienced at least one gastrointestinal adverse event

These biotech peptides are commonly explored for their potential roles in weight loss, skin health, and overall collagen peptide benefits

Since patients who are HbS heterozygous and have around 30% circulating fetal hemoglobin seldom have the severe clinical course linked to SCD, this is expected to be effective [81,82,83,84]

Our team can provide full support and guidance on regulatory compliance