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Subjects immediately reported a feeling of sleep pressure, and total sleep time increased by 59% (median) within a 130-minute interval compared to placebo

Epub 2013 Jun 28

The lack of adequate cobalamin in the body hinders the regeneration of tetrahydrofolate, which eventually leads to megaloblastic anemia due to the functional folate deficiency.On the other hand, the methylmalonyl-CoA mutase helps to metabolize odd chain fatty acids and branch chain amino acids.Cobalamin is also thought to keep the bodys level of sulfhydryl (SH) groups in reduced form