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Retrieved 14 May 2022, from A Proof of Concept, Phase IIa, Open Label Study to Evaluate the Safety and Efficacy of Subcutaneous Implants of Afamelanotide in Patients with Xeroderma Pigmentosum (XP)

Notably, 68% of subjects reported increased sexual desire with MT-II compared to only 19% with placebo

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Tissues were homogenized using a micropestle (Sigma), followed by sonication, incubation for 10 min on ice, centrifugation at 10,000 g and collection of supernatants