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In this PCOS model of gestational androgenization, treatment with GLP1/GIP improved glucose handling, fasting glucose levels and insulin sensitivity, as denoted by ITT and HOMA-IR, as well as circulating insulin concentrations (Fig

The analysis showed promising results in the reduction of HbA1C levels, but further research is needed to draw significant benefits

Status: Off-label clinical use Not FDA-approved for these indications Nightly SC injection Caveat: GH secretagogues affect insulin sensitivity

Therefore, prevention or impairment of oxidative stress constitutes a therapeutic target to be achieved for hepatoprotection