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One notable study focused on patients with type 2 diabetes who also suffered from chronic back pain

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Patients were excluded if they had an opioid-involved overdose in the 9 months prior to study entry

She told me a major concern with compounded drugs is the lack of reliability around dose, formulation and source. She also explained that these unapproved products do not come with warning labels that advise their providers of the risks of taking the drug. This raises questions over true informed consent for patients