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GLP-1 Agonism : GLP-1 enhances insulin secretion in response to meals, decreases glucagon secretion (which raises blood sugar), slows gastric emptying, and promotes feelings of fullness

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GLP-1 medications address some of these limitations by modulating the reward value of food and slowing gastric emptying, which creates physical fullness independent of appetite suppression

During the subsequent 17-week off-treatment period, the patients began to regain weight and showed some increases in type 2 diabetes progression, resulting in a 88% diabetes risk reduction after the off-period

The temperature should be 36F to 46F (2C to 8C)