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PT-141 does not interact adversely with ethanol and has no severe interactions with prescription medications

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This is why a gradual escalation over 4-8 weeks is used to reduce the severity of adverse gastrointestinal effects compared to a rapid 2-week jump

doi: 10.3389/fimmu.2026.1705839 Received 15 September 2025 Revised 07 March 2026 Accepted 09 March 2026 Published 30 March 2026 Volume 17 - 2026 Edited by Nirianne Querijero Palacpac, Osaka University, Japan Reviewed by Alba Marina Gimenez, University of So Paulo, Brazil Urszula Krzych, Walter Reed Army Institute of Research, United States Updates Copyright 2026 Tandel, Thakkar, Ahuja, Shah, Trivedi, Pied, Singh, Prajapati, Tyagi and Dalai