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A prior Phase 2a study assessing bimagrumab in patients with obesity and type 2 diabetes showed a 21.9% reduction in fat mass after 48 weeks of therapy while increasing lean muscle mass by 4.5%

Miss rates are low (historically under 5% for standard reviews, somewhat higher for priority reviews with complex clinical questions)

It may take some getting used to because it's not as easy as swallowing a pill, but the results are worth it

Specific genetic markers in the GLP1R, GIPR, FTO, and MC4R genes determine your baseline peptide sensitivity and predisposition to weight loss and metabolic improvement

When does one-time IV therapy make sense