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The mice were randomly divided into four groups: WT control group, APP/PS1 group, APP/PS1-ethanol group, and ethanol +NAC group
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Notably, co-treatment with mercury and N-acetylcysteine (NAC) significantly reduced Hg levels in both lung tissue (1.59-fold) and blood (1.71-fold) relative to the group exposed to mercury alone
Following exercise or exertion, patients with ME/CFS exhibit elevated levels of pro-inflammatory cytokines in peripheral blood, accompanied by muscle fatigue, exhaustion, and cognitive impairments, indicating that mitochondrial-driven inflammatory signaling may be a potential key driver of PEM symptoms (69)
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