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Excluding the few exceptions where methionine may act as a redox sensor (e } : CS1 maint: multiple names: authors list (link) "Life-span extension in mice by preweaning food restriction and by methionine restriction in middle age"
These reduce oxidative stress at the source
Telomere Shortening : Telomeres, the protective caps on the ends of chromosomes, shorten as we age, leading to cellular aging
Among the 4 high-grade serous epithelial ovarian cancer (HGSOC) cell lines: OV1369(R2), OV90, OV4453, and OV1946, the percentage of dead tumor cells after treatment with olaparib (10M) and ABT-263 (0.25 M for OV1369(R2) and 2.5 M for other cell lines) exceeded 75% [137]
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