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Increasing glutathione lowers free-radical damage in the lungs, which reduced the likelihood of developing COPD [62, 63]

Weakened Immune System: The immune-boosting properties of glutathione may also diminish, potentially making the body more susceptible to infections and illnesses

It thus involves well-regulated mechanisms mainly executed by macrophages in the whole body [222]

It exerts biological functions such as antioxidant and metabolic regulation through selenoproteins, which are key biomolecules

GSH, GSSG (enzymatic assays), 15LO1, GPX4, SLC7A11, and T2 biomarkers (Western blot and RNA-Seq) were measured in asthmatic and healthy control (HC) cells and fluids, with siRNA knockdown as appropriate