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The combination therapy of GLP-1 receptor agonists and metformin demonstrates superior safety over monotherapy, while revealing novel adverse events and demographic-specific risk patterns, thereby offering reliable evidence to inform clinical practice

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123 The native glucagon peptide stimulates cAMP production, and elevated cAMP levels in rat hepatocytes indirectly reduce CYP2C11 expression

The calculated uptake rate of LAAM GSH-CQDs from flow cytometry results revealed that most tumor cells had an uptake rate of up to 99%, whereas the average rate for normal cells was close to 10% (Fig