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Cleveland Clinic Journal of Medicine
If you're resistant to GLP-1, you're not getting its appetite-suppressing effects, which makes you more likely to eat more junk food, which only adds to the blood sugar problems that are keeping you resistant to GLP-1 in the first place
GLP-1 brands have been steadily expanding their reach through new indications, with Ozempic and Wegovy adding cardiovascular risk reduction in 2020 and 2024 respectively, and Zepbound adding obstructive sleep apnea in 2024
Liraglutide week-by-week timeline Week 1 (0.6mg): Most people notice mild appetite reduction within the first few days
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